NEW COMPOUNDS AS POTENTIAL INDUCERS OF TERMINAL DIFFERENTIATION OF TUMOR CELLS, A PHARMACEUTICAL COMPOSITION BASED ON SAID Russian patent published in 1999 - IPC

FIELD: organic chemistry, pharmacy. SUBSTANCE: invention proposes compounds of the formula: R₁-C(O)-(CH₂)₂-C(O)-R₂ where each of substitutes R₁ and R₂ has similar of distinct values being independently each of other; if R₁ and R₂ are similar then each of them has nonsubstituted or substituted arylamino-, cycloalkylamino-, pyridylamino-, piperidino-, 9-purine-6-amino- or thiazolylamino-group; if R₁ and R₂ are different then R₁ means group R₃-N-R₄ where R₃ and R₄ are similar or distinct being independently each of other and each means - H, OH, nonsubstituted or substituted, linear or branched alkyl, alkenyl, cycloalkyl, aryl, alkylhydroxy-, arylhydroxy-, arylalkylhydroxy-, pyridyl group; or R₃ and R₄ form together piperidine group and R₂ means hydroxylamino-, -OH, NH₂, alkylamino-, dialkylamino-, alkoxy-group; n = 4-8. Synthesized compounds are used for preparing a pharmaceutical composition that inhibits tumor cells proliferation. EFFECT: new compounds indicated above, enhanced effectiveness of compounds. 20 cl, 2 tbl