METHOD OF ENHANCEMENT OF CHEMOTHERAPEUTIC AGENT CYTOTOXICITY, SET FOR TREATMENT Russian patent published in 2000 - IPC

FIELD: medicine. SUBSTANCE: invention relates to method of enhancement of cytotoxicity of chemotherapeutic agent with respect to solid tumors exhibiting sensitivity in treatment with chemotherapeutic agent. Method involves administration of benzotriazine derivative to mammal bearing this tumor that enhances the cytotoxicity of chemotherapeutic agent being this administration is carried out 0.5-24 h before the latter agent. Invention relates to also the set used for treatment of patients bearing these tumors that contains chemotherapeutic agent and 1,2,4-benzo-triazine oxide taken at amount enhancing cytotoxicity of chemotherapeutic agent. EFFECT: broadened arsenal of agents used for treatment of solid tumors. 11 cl, 2 dwg, 19 ex