CONDENSED BENZAZEPINE DERIVATIVE, AN INTERMEDIATE COMPOUND FOR ITS SYNTHESIS, A PHARMACEUTICAL COMPOSITION Russian patent published in 1999 - IPC

FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to derivative of benzazepine with condensed nitrogen-containing aromatic 5-membered cycle of the formula (I) . Symbols in formula have the following values: ring B - nitrogen-containing aromatic 5-membered cycle having at least 1 nitrogen atom and optionally 1 oxygen or sulfur atom that can has optionally substituent(s); R¹,R² are similar and mean hydrogen atom; A - a single bond; group of the formula -NHCO-(CR³R⁴)_n-,; n = 0 or 1; R³,R⁴ can be similar or distinct and each means hydrogen atom, lower alkyl group (under condition that R³ and R⁴ can form together a lower alkylene group having from 2 to 7 carbon atoms), and ring C - benzene ring that can has optionally substituent(s), and its salts. Invention relates to also an intermediate compound used for synthesis of these compounds and to pharmaceutical compositions containing these compounds as an active component. Synthesized compounds are useful as antagonists of argininevasopressin. EFFECT: improved method of synthesis. 9 cl, 30 tbl, 41 ex