FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to compounds of the formula (I) 
where n is a whole number from 1 to 3; A is a fragment of 5-membered aromatic heterocycle containing at least one nitrogen atom which is bound through carbon atom which is an adjacent with heterocyclic nitrogen atom and can be substituted with lower alkyl, C3-C6-cycloalkyl, phenyl, naphthyl or aromatic 5-membered heterocycle containing oxygen or sulfur atom; 
is a simple bond or a double bond, or their pharmacologically acceptable salts and methods of their synthesis and a pharmaceutical composition on their basis showing hypoglycemic and hypolipidemic activity. Invention can be used in medicine as a drug for treatment of diabetic patients. EFFECT: improved method of synthesis, compounds are used as drugs. 11 cl, 10 tbl, 74 ex
| Title |
Year |
Author |
Number |
| THIENOPYRIMIDINE COMPOUNDS, METHOD OF PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION |
1996 |
- Suiti Furuja
- Nobuo Tokh
- Koiti Kato
- Sudzi Khinuma
|
RU2158739C2 |
| QUINOLINE DERIVATIVES, METHOD OF THEIR SYNTHESIS AND ANTI-INFLAMMATORY AGENT |
1994 |
- Takesi Sokhda
- Kharukhiko Makino
- Atsuo Baba
|
RU2132330C1 |
| METHOD OF PRODUCING DERIVATIVES OF THIOZOLIDINEDIONE OR THEIR SODIUM SALTS |
0 |
- Kanadzi Meguro
- Takesi Fudzita
|
SU1496634A3 |
| DERIVATIVES OF AZOLE, METHODS OF THEIR SYNTHESIS AND ANTIFUNGAL AGENT |
1994 |
- Katsumi Iton
- Kendzi Okonogi
- Akikhiro Tasaka
|
RU2131417C1 |
| METHOD OF PRODUCING DERIVATIVES OF THIAZOLIDINDION |
0 |
- Kanadzi Meguro
- Takesi Fudzita
|
SU1436876A3 |
| AMINOCUMARAN DERIVATIVES OR SALTS THEREOF, METHODS OF PREPARATION THEREOF, COMPOSITION FOR INHIBITING FORMATION OF LIPOPEROXIDE |
1992 |
- Tetsuja Aono[Jp]
- Sigenori Okhkava[Jp]
- Takajuki Doi[Jp]
|
RU2087473C1 |
| METHOD OF PRODUCING DERIVATIVES OF VINYLCARBOXYLIC ACIDS |
0 |
- Sini Tekao
- Kokhei Nisikava
|
SU1266470A3 |
| DERIVATIVE OF DI- AND TRIAZOLYLPROPANE, METHODS OF ITS SYNTHESIS AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF |
1996 |
- Katsumi Itokh
- Kendzi Okonogi
- Akikhiro Tasaka
|
RU2145605C1 |
| DERIVATIVES OF 2,4-OXAZOLIDINEDIONE OR THEIR PHARMACEUTICALLY ACCEPTABLE SALT, METHODS OF SYNTHESIS, MEDICINAL COMPOSITION SHOWING HYPOGLYCAEMIC AND HYPOLIPIDEMIC EFFECT, METHOD OF BLOOD GLUCOSE AND LIPID CONTENT DECREASE IN MAMMALIAN WITH DIABETES MELLITUS OR HYPERLIPIDEMIA |
1994 |
- Takasi Sokhda
- Khitosi Ikeda
- Ju Momose
- Satiko Imai
|
RU2126797C1 |
| DERIVATIVES OF TETRAZOLE, METHOD OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITIONS BASED ON THEM |
1994 |
- Takasi Sokhda
- Khitosi Ikeda
- Jju Momose
|
RU2144533C1 |
