DERIVATIVES OF THIAZOLIDINEDIONE, THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITION Russian patent published in 1999 - IPC

Abstract RU 2129553 C1

FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to compounds of the formula (I) where n is a whole number from 1 to 3; A is a fragment of 5-membered aromatic heterocycle containing at least one nitrogen atom which is bound through carbon atom which is an adjacent with heterocyclic nitrogen atom and can be substituted with lower alkyl, C₃-C₆-cycloalkyl, phenyl, naphthyl or aromatic 5-membered heterocycle containing oxygen or sulfur atom; is a simple bond or a double bond, or their pharmacologically acceptable salts and methods of their synthesis and a pharmaceutical composition on their basis showing hypoglycemic and hypolipidemic activity. Invention can be used in medicine as a drug for treatment of diabetic patients. EFFECT: improved method of synthesis, compounds are used as drugs. 11 cl, 10 tbl, 74 ex

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RU 2 129 553 C1

Authors

Takasi Sokhda

Khitosi Ikeda

Satiko Imaj

Ju Momose

Dates

1999-04-27—Published

1993-12-27—Filed