FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to derivative of di- and triazolylpropane of the formula (I) 
where Ar - optionally substituted phenyl group; R1, R2 - H or lower alkyl or R1 and R2 taken in common form lower alkylene group; R3 - H or acyl; X - nitrogen atom or acyl group; A means Y= Z (Y, Z have similar or different values and mean nitrogen atom or methine group optionally substituted with lower alkyl) or ethylene group optionally substituted with lower alkyl; n - the whole number from 0 to 1; Az - optionally substituted azolyl group or its salt that shows antifungal effect. EFFECT: improved method of synthesis. 26 cl, 16 tbl, 46 ex
| Title |
Year |
Author |
Number |
| DERIVATIVES OF AZOLE, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION |
1993 |
- Katsumi Itokh
- Kendzi Okonogi
- Norikazu Tamura
|
RU2116304C1 |
| DERIVATIVES OF AZOLE, METHODS OF THEIR SYNTHESIS AND ANTIFUNGAL AGENT |
1994 |
- Katsumi Iton
- Kendzi Okonogi
- Akikhiro Tasaka
|
RU2131417C1 |
| AZOLE COMPOUNDS, METHOD OF THEIR SYNTHESIS, ANTIFUNGAL PHARMACEUTICAL COMPOSITION AND METHOD OF TREATMENT OF FUNGAL INFECTION |
1998 |
- Itokh Katsumi
- Kitazaki Tomojuki
- Okonogi Kendzi
|
RU2189982C2 |
| DERIVATIVES OF 1,2,4-TRIAZOLO[1,5-B]PYRIDAZINE OR THEIR SALTS, METHODS OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION AND METHOD OF PATIENT TREATMENT |
1993 |
- Akio Mijake
- Jasukhiko Kavano
- Jasuko Asida
|
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| HETEROCYCLIC COMPOUNDS, PHARMACEUTICAL COMPOSITION SHOWING ANTAGONISTIC ACTIVITY WITH RESPECT TO ANGIOTENSIN-II AND A METHOD OF ANTAGONIZATION OF ANGIOTENSIN-II IN MAMMALS |
1992 |
- Takekhiko Naka[Jp]
- Esijuki Finada[Jp]
|
RU2104276C1 |
| HETEROCYCLIC COMPOUNDS, METHOD OF PREPARATION THEREOF, COMPOSITION BASED THEREON AND METHOD OF COUNTERACTION AGAINST TACHYKININ RECEPTORS |
1994 |
- Khideaki Natsugari
- Takenori Iskhimaru
- Takajuki Doi
|
RU2135471C1 |
| THIENOPYRIMIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITION |
1994 |
- Suiti Furuja
- Nobuo Tokh
- Tetsuja Okhtaki
- Tosifumi Vatanabe
|
RU2142275C1 |
| DERIVATIVES OF 2,4-OXAZOLIDINEDIONE OR THEIR PHARMACEUTICALLY ACCEPTABLE SALT, METHODS OF SYNTHESIS, MEDICINAL COMPOSITION SHOWING HYPOGLYCAEMIC AND HYPOLIPIDEMIC EFFECT, METHOD OF BLOOD GLUCOSE AND LIPID CONTENT DECREASE IN MAMMALIAN WITH DIABETES MELLITUS OR HYPERLIPIDEMIA |
1994 |
- Takasi Sokhda
- Khitosi Ikeda
- Ju Momose
- Satiko Imai
|
RU2126797C1 |
| DERIVATIVES OF OXAZOLIDINEDIONE, THEIR SYNTHESIS (VARIANTS) AND PHARMACEUTICAL COMPOSITION |
1995 |
- Takasi Sokhda
- Khirojuki Odaka
- Jju Momoze
- Mitsuru Kavada
|
RU2144030C1 |
| DERIVATIVES OF TETRAZOLE, METHOD OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITIONS BASED ON THEM |
1994 |
- Takasi Sokhda
- Khitosi Ikeda
- Jju Momose
|
RU2144533C1 |
