COMPOSITION FOR DIAGNOSIS OF HUMAN HEPATITIS C (VARIANTS), METHOD AND SET FOR DETECTION OF ANTIBODIES TO HUMAN HEPATITIS C VIRUS Russian patent published in 1999 - IPC

FIELD: medicine, immunology. SUBSTANCE: invention relates to immune analysis of HCV (early called as non-A, non-B hepatitis virus). In part, invention relates to combination of HCV antigens ensuring to carry out immune analysis of the broad range with respect to HCV antibodies. These combinations consist of an antigen from domain C of polyprotein HCV and at least one additional HCV antigen from both domain NS3, domain NS4, domain S and from domain NS5. They exhibit the form of hybrid protein, simple physical mixture or separate antigens usually bound with the solid matrix. EFFECT: broadened range of immunological activity of HCV antigens combination as compared with that of any single HCV antigen. 10 cl, 2 tbl, 7 ex