FIELD: medicine, virology. SUBSTANCE: invention relates to materials and methods used for suppression of hepatitis C virus (but not hepatitis A and B viruses) infection spreading. Invention proposes polypeptides showing antigenic properties of hepatitis C virus and their fragments. Invention proposes the diagnostic reagent for detection of antibodies raised to hepatitis C virus, set for detection of antibodies raised to hepatitis C virus including diagnostic reagent and method of detection of antibodies raised to hepatitis C virus. Invention ensures to obtain reliable and prognostic agents used for assay of nucleic acids, antigens and antibodies associated with hepatitis C virus. EFFECT: polypeptide indicated above, improved method of detection of antibodies. 30 cl, 73 dwg, 19 tbl
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