FIELD: chemistry of peptides. SUBSTANCE: invention relates to linear or cyclic oligopeptides containing the primary amino acid sequence of the formula (I): Tyr-X-Phe-Leu-Z where X and Z - amino acids or their derivatives or their analogs where X and Z can be bound covalently and form a heterocyclic structure. When oligopeptide is linear one then X - Ser, Gly, Pro, D-Ala and Z - Glu or its amino-derivative; when oligopeptide is cyclic one then X - diaminobutyric acid, Lys, Orn and X - Glu or its amino-derivative. Oligopeptides of the formula (I) are useful potentially as analgetics for pain relief and person enhanced comfort. EFFECT: analgetic property of oligopeptides. 5 cl, 4 dwg, 2 tbl, 3 ex
