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(19)

RU

(11)

2 636 456

(13)

C2

(51)

IPC

C07K19/00(2006-01-01)

C07K14/565(2006-01-01)

C07K1/06(2006-01-01)

C07K1/113(2006-01-01)

C07K17/10(2006-01-01)

C07H3/06(2006-01-01)

A61K38/21(2006-01-01)

A61K47/36(2006-01-01)

A61P31/12(2006-01-01)

A61P35/00(2006-01-01)

(21) (22)

Application

2014116550, 2012-09-28

(24)

Start date

2012-09-28

(22)

Actual filing date

2012-09-28

(45)

Published

2017-11-23

(72)

Inventor

Sakamoto IdzumiFukae KadzukhiroTedzuka KatsunariTadzuru KejsukeMaeda MasatosiKadzikhara YasukhiroTsudzi Takasi

(73)

Holder

Glitek, Ink.

GLYCOSYLATED POLYPEPTIDE AND ITS PHARMACEUTICAL COMPOSITION Russian patent published in 2017 - IPC C07K19/00 C07K14/565 C07K1/06 C07K1/113 C07K17/10 C07H3/06 A61K38/21 A61K47/36 A61P31/12 A61P35/00 

Abstract RU 2636456 C2

FIELD: pharmacology.

SUBSTANCE: glycosylated polypeptide with a homogeneous structure of the sugar chain and having interferon-β activity is obtained synthetically.

EFFECT: sugar chain structure homogeneity and presence of sialic acid on the non-reducing end of the sugar chain increases the half-life of the glycosylated form of interferon in blood and improves its pharmacokinetic properties.

12 cl, 50 dwg, 2 tbl, 12 ex

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RU 2 636 456 C2

Authors

Sakamoto Idzumi

Fukae Kadzukhiro

Tedzuka Katsunari

Tadzuru Kejsuke

Maeda Masatosi

Kadzikhara Yasukhiro

Tsudzi Takasi

Dates

2017-11-23—Published

2012-09-28—Filed

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