METHOD OF "ORTOPHEN" TABLETTED FORM PRODUCING Russian patent published in 1999 - IPC

FIELD: chemical-pharmaceutical industry. SUBSTANCE: tabletted form of "Ortophen" is obtained by mixing an active preparation with a filling agent followed by wet granulation of the mixture, drying and powdering the granulate, dry granulating and pressing the granulate to make tablets. After pressing a film coating consisting of a mixture of oidragite L-100, medicinal talc, polyethylene oxide-4000, tropeolin-0 and an antifoaming agent taken at their ratio (as measured for one tablet), wt.-%: 72.50:14.50:7.20:3.60:2.20, respectively, is applied on tablets. Also, nonconditioned ground tablets of "Ortophen" are added to the mixture for granulate powdering at amount 1.9-2.0% of an active preparation mass. EFFECT: increased strength of tablets, prolonged time of their fitness up to 2 years. 2 cl, 1 ex