INDOLE DERIVATIVES AND THEIR PHARMACEUTICALLY ACCEPTABLE ACID-ADDITIVE SALTS, PHARMACEUTICAL PREPARATION ON SAID Russian patent published in 1999 - IPC

Abstract RU 2136662 C1

FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to new compounds of the general formula (I) where R1-R4 mean hydrogen, halogen atoms, lower alkyl or trifluoromethyl; R5 and R6 means hydrogen, halogen atoms, lower alkyl, trifluoro-methyl or lower alkoxy-group and R7 means lower alkyl and to also pharmaceutically additive salts of acids of compounds of the formula (I). These compounds are effective in treatment and prophylaxis of central nervous system disorders, for example, depressions, bipolar disorders, fear state, sleep disorder, sexual sphere disorders, psychosis, schizophrenia, migraines and other morbid states associated with headaches or other pains, disorders associated with personal experiences or obsessions, social phobia or panic attacks, psychic organic disorders, psychic disorders in childhood, aggressivity, age memory disorders, disorders of nervous system function relationship caused by traumas, cerebral hemorrhage, nervous-degenerative diseases, disorders of cardiovascular system (high arterial pressure, thrombosis, insult), gastroenteric disorders (dysfunction of gastroenteric tract motor capacity). EFFECT: enhanced effectiveness of compounds. 7 cl, 41 ex

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RU 2 136 662 C1

Authors

Mikhaehl' Bes

Dates

1999-09-10Published

1994-10-20Filed