FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to derivatives of pyrone of the formula (I) 
where X - the group OR1,NHR1,CO2R4,CH2R4 or CH2OR1; R1 = R4 or COR4; R2 - hydrogen atom, C5-6-cycloalkyl; R5 - hydrogen atom, C1-6-alkyl (other values see p. 1 of the claim) which are useful as antiviral agents, for treatment of infections caused by human immunodeficiency virus or other retroviruses eliciting activity of aspartylproteases. EFFECT: antiviral activity of compounds. 8 cl, 3 tbl, 223 ex
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