FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to derivatives of 3-(5-tetrazolylbenzyl)-aminopiperidine of the formula (I) 
where R1 is C1-4-alkoxy-group; R2 - a residue of the formula (a); R3 - H or halogen atom; R4, R5 - H, halogen atom, C1-4-alkyl, C1-4-alkoxy-group, CF3; R6 - H, C1-4-alkyl, (CH2)m-cyclopropyl, -S(O)nC1-4-alkyl, phenyl, NR7R8, CH2C(O)CF3 or CF3; R7, R8 - H, C1-4-alkyl or acyl; x = 0 or 1; n = 0, 1 or 2; m = 0 or 1, or their pharmaceutically acceptable salts or solvates which are strong and specific antagonists of tachykinins including P-substance and other neurokinins. EFFECT: improved method of synthesis, antagonists of tachykinins. 22 cl, 1 dwg, 45 ex
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