N-ALKYL-SUBSTITUTED ATP DERIVATIVES AND METHOD OF PREPARATION THEREOF Russian patent published in 1999 - IPC

FIELD: organic synthesis. SUBSTANCE: compounds of formula I (presented in description) are provided, wherein R¹ and R², independently, are hydrogen or halogen atom; R³ and R⁴, independently, are phenyl or C_1-6-alkyl optionally substituted by one or several OR⁵, C_1-6-alkylthio, NR⁶R⁷, COOR⁸ or halogen; R⁵,R⁶,R⁷ and R⁸, independently, are C_1-6-alkyl; and X is acid residue, and their pharmaceutically acceptable salts. Methods for preparing such compounds are also provided. Compounds I inhibit aggregation of platelets. EFFECT: extended choice of anticoagulation drugs. 9 cl, 1 tbl, 5 ex