FIELD: pharmaceutics.
SUBSTANCE: invention relates to individual compounds: methyl ether [3aR-[3aα,4α,6α(1R*,2S*),6aα]]-[[6-[7-[[2-(3,4-difluorophenyl)cyclopropyl]amino]-5-(propyltio)-3H-1,2,3-triazolo[4,5-d]-pyrimidine-3-yl]-tetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]acetic acid; [3aR-[3aα,4α,6α(1R*,2S*),6aα]]-6-[[7-[2-(3,4-difluorophenyl)cyclopropyl]amino]-5-(propiltio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-tetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]-ethanol; [3aR-[3aα,4α,6α(1R*,2S*),6aα]-6-[[7-[(3,4-difluorophenyl)cyclopropyl]amino]-5-(propiltio)-3H-1,2,3-triazolo-[4,5-d]pyrimidin-3-yl]-tetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol. Invention also describes other individual compounds.
EFFECT: obtaining novel compounds which are intermediate compounds for producing triazolo[4,5-d]pyrimidine, which in turn is used to treat diseases mediated by P2T receptor.
3 cl, 9 ex
| Title |
Year |
Author |
Number |
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2001 |
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|
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|
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|
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|
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|
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|
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|
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|
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