FIELD: organic chemistry, pharmacy, cosmetics. SUBSTANCE: invention relates to new bicyclic aromatic compounds of the general formula (I) where values R1,R2,R3, X and Ar are given in p. 1 of the invention claim. Compounds show activity with respect to cellular differentiation and proliferation and can be used in treatment of patients with dermatological sicknesses associated with keratinization damage. Compounds are used by topical or systemic route. Compounds of the formula (I) can be used for body hygiene and care for hair. Invention describes a pharmaceutical composition containing the above indicated compounds and using for the same purposes as compounds of the formula (I). EFFECT: enhanced effectiveness of compounds and compositions. 16 cl, 3 dwg, 27 ex
Authors
Dates
1999-09-27—Published
1996-11-29—Filed