METHOD OF PREPARING WATER-SOLUBLE VITAMIN PREPARATION AND METHOD OF PREPARING VITAMIN PREPARATION Russian patent published in 1999 - IPC

FIELD: pharmaceutical chemistry. SUBSTANCE: methods for preparing water-soluble vitamin ready- to-use forms leading to preparations containing fat-soluble and water-soluble vitamins together. In the method, homogenization is accomplished by introducing vitaminizing component into preheated surfactant at their molar ratio 1:(0.9-2.5), respectively. Desired product is obtained in the form of fat-soluble binary associate, which is then to nonionic water-soluble second surfactant preheated to temperature sufficient for dissolving binary associate, the two latter being taken in molar ratio 1: (0.9-2.5), respectively. Then aqueous phase is supplemented by either preheated to flowing state water- soluble binary associate or hot solution of fat-soluble binary associate in surfactant. Thereafter, aqueous phase is heated to 50-90 C. EFFECT: increased concentration and stability of vitamin preparations and improved their organoleptic properties. 7 cl, 13 ex