FIELD: pharmacy. SUBSTANCE: pharmaceutical composition of poorly soluble active agents has fatty acid polyglycerol esters or fatty acid sorbitan esters as solubilizing agents in the combination with lipophilic excipients and nonionic surface-active substances. The composition is obtained by mixing carrier components followed by dispersing the poorly soluble agent. Obtained composition exhibits the enhanced biological availability at oral administration. EFFECT: improved property of the composition. 13 cl
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Authors
Dates
1999-10-27—Published
1994-07-08—Filed