FIELD: organic chemistry, antibacterial agents. SUBSTANCE: invention relates to thiopyridines of the formula (I) where R1, R2 - H; R3 - H, C1-4-alkyl, C1-4-alkyl, C1-4-alkylcarbonyl, C2-4-alkenyl-carbonyl, halogen-C1-4-alkylcarbonyl or alkylsulfonyl that are substituted with R4; R4 is carboxy-group, C1-4-alkoxycarbonyl or -N(R14)R15; R15 - H, C1-4-alkyl or alkoxy-group; R6 is CmH2m-R6a radical where R6a - furan, thiophene, pyrrol, oxazole, isoxazole, thiazole, isothiazole, imidazole, pyrazole, triazole, tetrazole, thiadiazole, oxadiazole that can be substituted with R8 and R9 (other values see in p. 1 of the invention claim). Compounds are effective with respect to Helicobacter bacteria. EFFECT: new compounds indicated above, an antibacterial activity. 8 cl, 1 tbl, 13 ex
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Authors
Dates
1999-12-10—Published
1995-06-09—Filed