FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to substituted aminoalkylaminopyridines of the formula (I) where R1,R2 - H; R3 - halogen atom or alkyl; A, R4 - C1-7-alkyl; n = 0 or 1; X means N or CH; R5 is C1-7-alkyl or Ar-C1-4-alkyl; Ar - phenyl, naphthyl, furyl or phenyl substituted with R7,R8 and R9; or R5 and R6 in common with nitrogen atom to which they bound form possibly substituted 5-, 6- or 7-membered heterocycle. Compounds of the formula (I) are effective against bacterium Helicobacter that ensures to use their as active substances for treatment of patients with sicknesses caused by this bacterium species. EFFECT: enhanced effectiveness of bacterial infection. 6 cl, 1 dwg, 1 tbl, 21 ex
Title | Year | Author | Number |
---|---|---|---|
PYRIDYLTHIO-COMPOUNDS FOR CONTROL OF HELICOBACTER BACTERIUM | 1995 |
|
RU2149872C1 |
SUBSTITUTED ARYLALKYLTHIOALKYLTHIOPYRIDINES USED FOR CONTROL OF BACTERIUM HELICOBACTER | 1995 |
|
RU2139286C1 |
THIOPYRIDINES USED FOR CONTROL OF HELICOBACTER BACTERIA | 1995 |
|
RU2142459C1 |
IMIDAZO[1,2-A]PYRIDINE ALKOXYALKYLCARBAMATES AND DRUG BASED ON SAID | 1994 |
|
RU2139288C1 |
SUBSTITUTED ARYLTHIOALKYLTHIOPYRIDINES, METHOD OF THEIR SYNTHESIS, DRUG BASED ON THEREOF AND METHOD OF DRUG PREPARING | 1994 |
|
RU2154062C2 |
DIHYDROBENZOFURANS, METHOD OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITION ON SAID | 1995 |
|
RU2138498C1 |
IMIDAZOPYRIDINE AZOLIDINONES AND THEIR SALTS, DRUG | 1995 |
|
RU2138501C1 |
COMPOSITIONS CONTAINING AT LEAST SINGLE GLUCOCORTICOSTEROID IN COMBINATION WITH PULMONARY SURFACE-ACTIVE SUBSTANCE FOR TREATMENT OF NEWBORNS WITH RESPIRATORY DISTRESS-SYNDROME AND ADULTS WITH ACUTE RESPIRATORY DISTRESS-SYNDROME | 1995 |
|
RU2157222C2 |
PANTOPRAZOL-BASE MEDICINAL AGENT FOR ORAL ADMINISTRATION | 1992 |
|
RU2089180C1 |
POLYPEPTIDES SHOWING ACTIVITY OF PULMONARY SURFACE-ACTIVE SUBSTANCE AND PHARMACEUTICAL COMPOSITION | 1995 |
|
RU2145611C1 |
Authors
Dates
1999-08-27—Published
1994-11-26—Filed