SUBSTITUTED ARYLTHIOALKYLTHIOPYRIDINES, METHOD OF THEIR SYNTHESIS, DRUG BASED ON THEREOF AND METHOD OF DRUG PREPARING Russian patent published in 2000 - IPC

Abstract RU 2154062 C2

FIELD: organic chemistry, chemical technology, pharmacy. SUBSTANCE: invention relates to substituted arylthioalkylthio-pyridines of the formula (I) where R1-R4 mean hydrogen atom; R5 is hydrogen atom, (C1-C4)-alkyl or (C1-C4)-alkoxyl; R6 means cycle substituted by R8 and R9 that is taken among the group including benzene, thiazole, imidazole, triazole, tetrazole, thiadiazole, pyridine, pyridine-N-oxide, pyrimidine and benzimidazole; R7,R9,R11,R12 mean hydrogen atom or (C1-C4)-alkyl; R8 is hydrogen atom, NH2-group or (C1-C4)-alkyl possibly substituted with R10; m = 2-4; n, p, q = 0. Salts of synthesized compounds are effective for control of bacterium Helicobacter. EFFECT: improved method of synthesis, valuable antibacterial properties. 10 cl, 2 tbl, 24 ex

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RU 2 154 062 C2

Authors

Gerkhard Grundler

Jorg Zenn-Bilfinger

Vol'Fgang Opferkukh

Bernkhard Kol'

Dates

2000-08-10Published

1994-06-28Filed