METHOD OF PURIFICATION AND STORAGE OF, AQUEOUS SOLUTION OF PURIFIED FACTOR IX, COMPOSITION CONTAINING FACTOR IX, AND METHOD OF TREATMENT Russian patent published in 1999 - IPC

FIELD: clinical hematology. SUBSTANCE: invention provides new method for protection of blood coagulation factor IX against proteases during purification and storage of blood. High concentrations of one or more water-soluble organic and inorganic salts are used to stabilize factor IX contained in solutions obtained from blood plasma or in solutions obtained from other sources in order to prevent transformation of factor IX into clinically useless protein structures such as factor IX_a and/or degenerated factor IX proteins. EFFECT: increased stability of factor IX and discover ed high-activity factor IX preparations. 13 cl, 4 tbl, 8 ex