FIELD: organic chemistry, pharmacy. SUBSTANCE: invention describes new derivatives of pyrazole of the general formula (I) given in p. 1 of the invention claim. Compounds show an antagonistic activity with respect to corticotropin releasing-factor. They are effective for treatment of patients with broad pattern of diseases including diseases induced by stress. Invention describes also a pharmaceutical composition based on the above indicated compounds. EFFECT: enhanced effectiveness of derivatives and compositions. 7 cl, 2 tbl, 18 ex
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