FIELD: medicinal technics. SUBSTANCE: system contains carrier and self-gumming matrix. The latter contains, wt parts: ethylene-vinyl acetate copolymer, 40-60; cellulose material, 5-20; at least one compound selected from group including crotamitone, 2-pyrrolidone N-substituted by C1-C15-alkyl, cyclohexyl, or 2-hydroxyethyl, aliphatic C12-C20-alcohols, 35-55; and hormone containing estrogen components, proestrogen components, or their mixtures, 0.01-7. Invention also provides method of preparing such system. EFFECT: enhanced release of hormone. 12 cl, 4 dwg, 4 tbl, 16 ex
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Authors
Dates
2000-01-27—Published
1995-03-27—Filed