FIELD: pharmaceutical chemistry. SUBSTANCE: composition comprises (if necessary): desalting polymer matrix capable of forming flexible film on drying and selected from cellulose polymers or copolymers, or vinylpyrrolidone/vinyl acetate copolymers; active principle; promoter for transdermal absorption of active principle (15-30% of the total weight of composition); and nonaqueous physiologically acceptable solvent capable of dissolving desalting matrix and transdermal absorption promoter, which rapidly vaporizes when in contact with skin. EFFECT: achieved pulverizability of composition and resistance of active substance to hepatic enzymes. 37 cl, 15 tbl, 38 ex
Authors
Dates
2001-01-20—Published
1996-03-29—Filed