MONOCLONAL ANTIBODY BINDING WITH HEPATITIS B VIRUS SURFACE ANTIGEN, FAB-FRAGMENT AND METHOD OF DECREASE OF LEVEL OF CIRCULATING SURFACE ANTIGEN OF HEPATITIS B VIRUS ANTIGEN IN PATIENTS Russian patent published in 2000 - IPC

Abstract RU 2146706 C1

FIELD: medicine, immunology, virology. SUBSTANCE: invention relates to monoclonal antibody showing effectiveness for diagnosis and treatment of patients with hepatitis B. Monoclonal antibodies are obtained from the cells strain prepared by fusion of xenogenic hybridoma SPAZ-4 with blood cells of patient immunized with hepatitis B vaccine. Monoclonal antibodies eliciting the antihepatitis effect are used for protection of patients showing depressed immunity and for diagnosis of hepatitis B. EFFECT: enhanced effectiveness of monoclonal antibody. 5 cl, 2 dwg, 13 tbl, 9 ex

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RU 2 146 706 C1

Authors

Lars G.Ostberg

Dates

2000-03-20—Published

1992-11-06—Filed