FIELD: medicine, immunology, virology. SUBSTANCE: invention relates to monoclonal antibody showing effectiveness for diagnosis and treatment of patients with hepatitis B. Monoclonal antibodies are obtained from the cells strain prepared by fusion of xenogenic hybridoma SPAZ-4 with blood cells of patient immunized with hepatitis B vaccine. Monoclonal antibodies eliciting the antihepatitis effect are used for protection of patients showing depressed immunity and for diagnosis of hepatitis B. EFFECT: enhanced effectiveness of monoclonal antibody. 5 cl, 2 dwg, 13 tbl, 9 ex
| Title |
Year |
Author |
Number |
| HEPATITIS B VIRUS SURFACE ANTIGEN EPITOPE AND USE THEREOF |
2011 |
- Kim Se-Kho
- Khong Kvang-Von
- Shin Jong-Von
- Chang Ki Khvan
- Kim Min-Soo
- Im Dzung-Ae
|
RU2585525C2 |
| METHOD OF PREPARING SURFACE ANTIGEN OF HEPATITIS B VIRUS (HBS AG), MONOCLONAL ANTIBODIES CB-HEPI, SURFACE ANTIGEN OF HEPATITIS B VIRUS (HBS AG) AND METHOD OF PREPARING HYBRID CLONE 48/1/574 PRODUCING MONOCLONAL ANTIBODIES CB-HEPI |
1992 |
- Verena Lusila Musio Gonsales
- Ehduardo Penton Arias
- Kh'Juvel' Fontirrochi Ehskobar
- Marselo Nasabal' Gal'Ves
- Marta De Gonsales Gr'Ego
- Alekhandro Beldarrain Isnaga
- Gil'Ermo Padron Gonsales
- Viktoria Ramires Al'Bakhes
- Arnal'Do Garsia Pen'Ja
- Karlos Ehnrike Ruis Krus
- Gladis Mabel' Isk'Erdo Lopes
- Luis Ehrrera Martines
- Khose Garsia Suares
- Gustavo De Lja Riva De Lja Riva
- Ramon Aleksis Sant'Jago Avila
- Karlos Duarte Kano
- Lilia Peres Suares
|
RU2128707C1 |
| PREPARATION OF VACCINES CONTAINING HEPATITIS TYPE B VIRUS SURFACE ANTIGEN AND SURFACE-ACTIVE MATERIAL |
2006 |
|
RU2444374C2 |
| METHOD OF PREPARING HEPATITIS B SURFACE ANTIGEN PURIFIED PARTICLES, PURIFIED PARTICLE OF HUMAN HEPATITIS B SURFACE ANTIGEN AND VACCINE AGAINST HEPATITIS B |
1990 |
|
RU2080876C1 |
| ANTIBODIES AGAINST HEPATITIS B VIRUS AND THEIR USE |
2020 |
- Luo, Wenxin
- Jiang, Yichao
- Yu, Chao
- Chen, Xiaoqing
- Tang, Jixian
- Yuan, Quan
- Zhang, Tianying
- Xia, Ningshao
|
RU2803082C2 |
| NEW ANTIBODIES AGAINST HEPATITIS B VIRUS AND APPLICATION THEREOF |
2020 |
- Luo, Wenxin
- Wen, Can
- Xiang, Xinchu
- Tang, Jixian
- Wu, Yangtao
- Zhang, Tianying
- Yuan, Quan
- Xia, Ningshao
|
RU2814471C2 |
| AGENTS AND METHODS OF TREATING HEPATITIS B VIRUS |
2017 |
- Protser Ulrike
- Bauer Tanya
- Kosinska Anna
- Myuk-Khejsl Martin
|
RU2740802C2 |
| RECOMBINANT PLASMID DNA PKHBC-33 CONTAINING GENE OF HEPATITIS B VIRUS CORE ANTIGEN INVOLVING SEQUENCE OF THE MAIN NEUTRALIZING EPITOPE OF HEPATITIS B VIRUS SURFACE ANTIGEN (137-147) AND STRAIN OF BACTERIUM ESCHERICHIA COLI - A PRODUCER OF HEPATITIS B VIRUS CORE ANTIGEN WITH THE MAIN NEUTRALIZING EPITOPE OF HEPATITIS B VIRUS SURFACE ANTIGEN EXHIBITED ON ITS SURFACE |
1995 |
- Karpenko L.I.
- Chikaev N.A.
- Melamed N.V.
- Il'Ichev A.A.
- Bajborodin S.I.
|
RU2112039C1 |
| APPLICATION OF SANGLIFERIN FOR TREATING HEPATITIS C VIRUS |
2006 |
- Lin Kaj
- Uehjdmann Bit
- Tsimmermann Kaspar
|
RU2427372C2 |
| RECOMBINANT PLASMID DNA PVAX2 FOR TRANSFER AND EXPRESSION OF HEPATITIS B SURFACE ANTIGEN GENE IN VARIOLOVACCINE VIRUS GENOME AND A STRAIN OF VARIOLOVACCINE VIRUS EXPRESSING THE SURFACE ANTIGEN OF HEPATITIS B VIRUS |
1985 |
- Al'Tshtejn A.D.
- Andzhaparidze O.G.
- Antonova T.P.
- Baev A.A.
- Bendukidze K.A.
- Gorodetskij S.I.
- Zakharova L.G.
- Krjazhevskaja M.V.
- Pashvykina G.V.
- Fodor I.I.
- Chernos V.I.
|
SU1354709A1 |
