NUCLEIC ACID SYNTHETIC MOLECULE (VERSIONS), MAMMAL CELL EXPRESSION VECTOR, MAMMAL HOST CELL AND METHOD OF EXPRESSING ANTIGEN PROTEIN OF HUMAN EPIDERMAL GROWTH FACTOR-2 (HER2/neu) OR SHORTENED FORM THEREOF Russian patent published in 2010 - IPC C12N15/12 C12N15/63 C12N15/861 C12N1/00 C12N5/00 C12P21/02 A61K48/00 A61K39/00 A61P35/00 

Abstract RU 2397249 C2

FIELD: chemistry; biochemistry.

SUBSTANCE: invention relates to genetic engineering and can be used to optimise expression of the antigen protein of the human epidermal growth factor-2 (HER2/neu). To obtain the HER2/neu protein, a nucleic acid synthetic molecule is used, which is codon-optimised for high level of expression of the said protein in a human cell.

EFFECT: invention increases production of the recombinant HER2/neu protein during expression in human cells.

8 cl, 10 dwg, 14 ex

Similar patents RU2397249C2

Title Year Author Number
FUSED PROTEIN OF TELOMERASE REVERSE TRANSCRIPTASE, NUCLEOTIDES CODING THEM, AND USING THEM 2007
  • Chiliberto Dzhennaro
  • La Monika Nikola
  • Mennuni Karmela
  • Skarselli Ehliza
RU2473691C2
FUSED PROTEINS OF CARCINOEMBRYONAL ANTIGEN 2005
  • La Monika Nikola
  • Fachch'Jabene Andrea
  • Aurisichch'O Luidzhi
  • Chiliberto Dzhennaro
RU2380375C2
NUCLEIC ACID SEQUENCE ENCODING HIV-1 GAG PROTEIN, METHOD FOR ITS PREPARING, VECTOR CONTAINING THEREOF, PROTEIN ENCODED BY ITS, PHARMACEUTICAL COMPOSITION AND THEIR USING IN PROPHYLAXIS AND/OR TREATMENT OF HIV-INFECTION AND AIDS 2002
  • Biton Ehndrju
  • Ehrtl Piter Frants
  • Gof Dzherald Uehjn
  • Lir Ehndrju
  • Tajt Dzhon Filip
  • Van Uili Kehtrin Ehnn
RU2312896C2
RECOMBINANT VACCINE OF FELINE LEUKEMIA VIRUS CONTAINING OPTIMISED GENE OF FELINE LEUKEMIA VIRAL ENVELOPE 2012
  • Pule Erve
  • Khajdmann Teri
RU2591817C2
SIMIAN ADENOVIRUS NUCLEIC ACID- AND AMINO ACID-SEQUENCES, VECTORS CONTAINING SAME, AND USE THEREOF 2010
  • Kolloka Stefano
  • Nikosija Alfredo
  • Korteze Rikkardo
  • Ammendola Virdzhinija
  • Ambrozio Marija
RU2604815C2
F-PROTEIN OF RESPIRATORY SYNCYTIAL VIRUS AND ITS USE 2007
  • Grjunval'D Tomas
  • Juberla Klaus
RU2464316C2
ANTI-HCV VACCINE 2003
  • Brett Sara
  • Khehmblin Pol Ehndrju
  • Ogilvi Luiz
RU2323744C2
VACCINE COMPOSITION 2014
  • Stojdl Devid F.
  • Bell Dzhon Kemeron
  • Likhti Brajan
  • Pol Dzhonatan
RU2684211C2
VECTORS CONDITIONALLY EXPRESSING THERAPEUTIC PROTEINS, HOST CELLS COMPRISING THE VECTORS, AND USES THEREOF 2011
RU2612788C2
OPTIMISED EXPRESSION OF HPV 58 L1 IN YEAST 2004
  • Brajan Dzhanin T.
  • Braunlou Mishell K.
  • Shul'Ts Loren D.
  • Van Sin'-Min'
  • Jansen Katrin U.
RU2370538C2

RU 2 397 249 C2

Authors

Gallo Paskual'

Monachi Paolo

Nutstso Mauritsio

Dates

2010-08-20Published

2004-07-20Filed