METHOD OF SYNTHESIS OF BETULINOL DIACETATE Russian patent published in 2000 - IPC

FIELD: organic synthesis, chemical technology. SUBSTANCE: invention describes method of synthesis of betulinol diacetate by acetylation of betulinol in the presence of catalyst at heating. Acetylation is carried out with mixture of acetic acid and C₁-C₄-alcohol acetates at simultaneous removal of water from reaction mixture by the known methods. Method ensures to avoid the use of expensive and toxic reagents (acetic anhydride, pyridine, benzene). EFFECT: simplified technology, decreased cost and hazard of production. 4 cl, 2 tbl, 7 ex