FIELD: medicine, biotechnology, pharmacology. SUBSTANCE: method involves disintegration of pig brain subjected preliminary to modeling bilateral hemorrhagic insult, tissue homogenization in medium (pH = 7.3-7.6), separation of insoluble enzymes homogenate, extraction with hexane from obtained liquid of lipid components followed by clearing and sterilizing filtration and lyophilization of the end product frozen at -30 C. Obtained agent shows the presence of specific traumotrophic peptides (molecular mass is 400-1 500 Da) and dominating amino acids as aspartic, glutamic acids, alanine, glycine and serine. EFFECT: new quality composition of agent, high activity, enhanced effectiveness of treatment, broadened arsenal of drugs used for treatment of patients with insult. 3 cl, 3 tbl, 1 ex
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Authors
Dates
2000-06-27—Published
1998-08-05—Filed