FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to substituted phenylimidazolidines of the formula (I) 
where Y is O or NH; Z2 is CF3; Z1 is cyano- or nitro-radical; X is O or S; R3 is H or alkyl possibly substituted with halogen atom or cyano-radical R4, R5 is alkyl possibly substituted with hydroxy 1 that can be protected in all possible isomeric, racemic, enentiomeric and diasteriameric forms and acidic or basic salts that show anti-androgenic activity. EFFECT: improved method of synthesis, valuable pharmacological properties. 8 cl, 38 ex
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Year |
Author |
Number |
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1993 |
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1995 |
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RU2174513C2 |
