FIELD: medicine, pharmacy. SUBSTANCE: invention proposes the oral agent as granules or tablets made of core, water-soluble intermediate layers and external layer showing stability to gastric juice. Tablet core has pantoprazol as an active component in combination with buffer inorganic basic compound, preferably, sodium carbonate, and binding agent - polyvinylpyrrolidone and/or hydroxypropylmethylcellulose, and filling agent - mannitol. Granule has pantoprazol and polyvinylpyrrolidone and/or hydroxypropylmethylcellulose. EFFECT: improved quality and property of agent. 6 cl
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