FIELD: chemical industry. SUBSTANCE: described is method of preparing hemcitabin hydrochloride which comprises removing protecting group from β-1-(2'-deoxy-2,2'- difluoro-3', 5'-di-o-benzoyl-D-ribofuranosyl)-4- aminopyrimidin-2-one in the presence of base and alcohol and subsequently treating the resulting solution with hydrochloric acid and antisolvent and isolating the resulting solid product. EFFECT: more efficient process and increased yield of the desired product. 12 cl, 5 ex
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