17-DIFLUOROMETHYLENE-EXTRATRIENES: COMPOUNDS AND METHOD OF PREPARATION THEREOF Russian patent published in 2000 - IPC

Abstract RU 2155770 C2

FIELD: organic synthesis. SUBSTANCE: invention provides novel difluoromethylene compounds of general formula I: (I), in which R¹ is hydrogen atom or C₁-C₁₀-alkyl; R⁵ methyl or ethyl; R² hydrogen atom or C₁-C₁₀-alkyl in alpha- or beta- position; R³ hydrogen or C₁-C₁₀-alkoxy in alpha- or beta-position; R⁴ hydrogen in alpha- or beta-position; A,B,D,E, and G each are hydrogen atom and, if necessary, at least one of substituent pairs G and R², R² and R⁴, R⁴ and A, A and R³, D and E form double bond. Compound I exhibit antioxidant and vessel-protection properties and can be used for treatment and prophylaxis of a variety of afflictions. EFFECT: expanded assortment of useful biologically-active compounds. 12 cl, 2 dwg, 12 ex

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RU 2 155 770 C2

Authors

Rol'F Bol'Mann

Gabor Rubanil

Dates

2000-09-10—Published

1996-03-13—Filed