FIELD: molecular biology, biotechnology. SUBSTANCE: invention relates to technology of production of proteins using recombinant strains of yeast Yarrowia lipolytica. Invention proposes nucleotide sequences of gene XPR2: signal, sequence pro-1, sequence pro-2, promoter, terminating sequence. Also, invention proposes strains of yeast Yarrowia lipolytic producing prorenin and human anaphylatoxin C5a. EFFECT: high quality of end product in easily separatable form. 16 cl, 17 dwg, 8 tbl, 3 ex
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