FIELD: medicine. SUBSTANCE: method involves administering effective quantity of nitrogen-containing heterocyclic compound to a mammalian having need in it. Compound of formula 1 is applied as the nitrogen-containing heterocyclic compound, where R1-R9 adopt some values shown in the invention description, or its appropriate salt, or hydrate having their pharmaceutical or contraceptive composition on their base. EFFECT: wide set of inhibitor compounds. 13 cl, 9 dwg, 3 tbl
Title |
Year |
Author |
Number |
METHODS OF INHIBITION OF TYROSINE KINASE ACTIVITY IN EPIDERMAL GROWTH FACTOR RECEPTORS, BICYCLIC PYRIMIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITION SHOWING ACTIVITY INHIBITING ACTIVITY OF TYROSINE KINASE IN EPIDERMAL GROWTH FACTOR RECEPTORS AND COMPOSITION ELICITING CONTRACEPTIVE EFFECT |
1995 |
- Aleksander Dzhejms Bridzhes
- Uilliam Aleksander Dehnni
- Dehvid Fraj
- Alan Krejker
- Robert Majer
- Gordon Uilliam R'Jukastl
- Ehndrju Mark Tompson
|
RU2174980C2 |
DERIVATIVES OF INDOLE, THEIR TAUTOMERS, MIXTURES OF THEIR ISOMERS OR SEPARATE ISOMERS AND PHARMACEUTICALLY ACCEPTABLE SALTS, PHARMACEUTICAL COMPOSITION SHOWING ANTITUMOR OR INHIBITING PROTEIN TYROSINE KINASE ACTIVITY AND METHOD OF INHIBITION OF PROTEIN TYROSINE KINASE-DEPENDING DISEASE OR CONTROL OF ABERRANT GROWTH OF MAMMALIAN OR HUMAN CELLS |
1993 |
- Dobrasin Ehllen Mira
- Shovol'Ter Khovord Dehniel' Khollis
- Denni Uilliehm Aleksander
- Pal'Mer Brajn Desmond
- Rjukasel' Gordon Uilliehm
- Tersel' Moehna
- Tomson Ehndrju Mark
|
RU2155187C2 |
METHOD OF SYNTHESIS OF (S)-(-)- AND (R)-(+)-ISOMERS OF (5-AMINO-1,2-DIHYDRO-2-METHYL-3-PHENYLPYRIDO-[3,4-B]-PYRAZINE- -7-YL)-CARBAMIDE ACID ETHYL ESTER OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS AND INTERMEDIATE (S)-(-)- AND (R)-(+)-ISOMERS OF [6-AMINO-4-[[2-(ALKOXYALKYLAMINO)-1-METHYL-2-OXOETHYL]-AMI- -NO]-5-NITRO-2-PYRIDINYL]-CARBAMIDE ACID ETHYL ESTER |
1994 |
- Om Prakash Goehl[Us]
- Sham Shridkhar Nikam[In]
|
RU2098409C1 |
METHOD OF PREPARING TRANS-6-[SUBSTITUTED PYRROL-1- YL)ALKYL]PYRAN-2-ON DERIVATIVES AND THEIR DIHYDROXY-CONTAINING ACIDS AND SALTS, HYDROXY-, 1,3-DIOXAN- OR PYRROLE-CONTAINING CARBOXYLIC ACIDS AS INTERMEDIATES FOR PREPARING SAID PYRAN-2-ON DERIVATIVES |
1994 |
- Donal'D Ehjdzhin Batler
- Tung Van Li
- Tomas Norman Nanninga
|
RU2138497C1 |
EPIDERMAL GROWTH FACTOR RECEPTOR INHIBITORS |
2022 |
- Iakobson Georgii Viktorovich
- Kadyrov Shamil Dinarovich
- Smetanin Ilia Alexeevich
- Khaidarov Adel Ravilevich
- Khalabudin Dmitry Alekseevich
- Sidorova Kseniia Sergeevna
- Zavialov Kirill Vadimovich
- Polianczyk Daniel Evgenevich
- Morozov Dmitry Valentinovich
|
RU2821531C2 |
ARYLTHIOCOMPOUNDS, METHOD OF TREATMENT AND PHARMACEUTICAL COMPOSITION |
1995 |
- Dzhon Majkl Domadzhela
- Ehdvard Fejtz Ehlslejdzher
- Rokko Din Dzholiotti
|
RU2156236C2 |
DERIVATIVES OF 6-ARYLPYRIDO[2,3-D]PYRIMIDINES AND -NAPHTHYRIDINES, PHARMACEUTICAL COMPOSITION SHOWING INHIBITORY EFFECT ON CELLULAR PROLIFERATION INDUCED BY PROTEIN TYROSINE KINASE AND METHOD OF INHIBITION OF CELLULAR PROLIFERATION |
1995 |
- Blanklej Klifton Dzhon
- Doehrti Annet Mehriehn
- Khambej Dzhejms Marino
- Panek Robert Li
- Shreder Mehl Konrad
- Shovol'Ter Khovard Dehniel' Khollis
- Konneli Klio
|
RU2191188C2 |
DERIVATIVES OF BENZOTHIOPHENE, BENZOFURAN, INDOLETHIAZEPINONE, OXAZEPINONE AND DIAZEPINONE, PHARMACEUTICAL COMPOSITION SHOWING ACTIVITY INHIBITING CELLULAR ADHESION OR HIV-ACTIVITY, METHOD OF INHIBITION OF LEUKOCYTE ADHESION TO ENDOTHELIAL CELLS IN TREATMENT OF DISEASES CAUSED WITH ITS, METHOD OF TREATMENT OF MAMMALS INFECTED WITH HIV-INFECTION |
1995 |
- Dajehn Khehrris Boskelli
- Dejvid Tomehs Konnor
- Dzhejmz Bernard Krejmer
- Pol Charlz Anehngst
|
RU2144033C1 |
SULFAMIC ACID ESTERS, PHARMACEUTICAL COMPOSITION FOR CONTROL OF CHOLESTEROL CONCENTRATION, METHOD OF TREATMENT OF PATIENTS WITH HYPERCHOLESTEROLEMIA, METHOD OF TREATMENT OF PATIENTS WITH ATHEROSCLEROSIS |
1994 |
- Khelen Tsenvej Li
- Dzhozef Armend Pikard
- Drago Robert Sliskovits
- Vendell Virendzhe
|
RU2137756C1 |
FIBROBLAST GROWTH FACTOR RECEPTOR INHIBITORS |
2014 |
- Bifalko Nil
- Dipetro Lusian V.
- Khodaus Brajan L.
- Miduturu Chandrasekkhar V.
|
RU2704112C2 |