FIELD: pharmaceutical chemistry. SUBSTANCE: invention provides novel polypeptide having following sequence: 
, where X1 and 
each are Cys or Val and X3 is Thr or Lys but X1 and X2 cannot be both Cys when X3 is Thr, and also salts and functional derivatives thereof. Polypeptide according to invention exhibits essentially the same activity as p277 but it is significantly more stable. EFFECT: enlarged resource of polypeptides with antidiabetic activity. 17 cl, 9 tbl, 11 ex
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