Patenton — panteon of patents

(19)

RU

(11)

2 159 809

(13)

C1

(51)

IPC

(21) (22)

Application

99111219/13, 1999-05-25

(24)

Start date

1999-05-25

(22)

Actual filing date

1999-05-25

(45)

Published

2000-11-27

(72)

Inventor

Kiseleva I.V.Aleksandrova G.I.Rudenko L.G.Naumenko Z.S.Klimov A.I.

(73)

Holder

Nauchno-Issledovatel'Skij Institut Ehksperimental'Noj Meditsiny Ramn

INFLUENZA VIRUS STRAIN A/47/SYDNEY/97/14 (H3N2) FOR PRODUCTION OF LIVE INFLUENZAL INTRANASAL VACCINE FOR BABIES Russian patent published in 2000 - IPC

Abstract RU 2159809 C1

FIELD: applied microbiology. SUBSTANCE: vaccinal strain A/47/Sydney/97/14 (H3N2), which is reassortant, is obtained by cross-breeding of epidemic virus A/Sydney/5/97/ (H3N2) with cold-adapted temperature-sensitive virus A/Leningrad/134/47/57 (H2N2), which is attenuation donor. Strain A/47/Sydney/97/14 (H3N2) actively multiplies in developing chicken embryos at optimal temperature 34 C. Strain is characterized by temperature sensitivity and cold adaptability. Reassortant inherits two genes from epidemic virus, which encode surface proteins (gemmagglutinin and neuraminidase). It also receives six genes encoding non-glycosylated proteins from attenuation donor. In addition, the strain does non induce immune response in babies during intranasal injection. Biological properties and low degree of immunoreactivity meet requirements for vaccine strains. EFFECT: enabled prophylactics of epidemic influenza provoked by specific antigenic virus species. 1 tbl

Similar patents RU2159809C1

Title Year Author Number
INFLUENZA VIRUS STRAIN A/17/SYDNEY/97/76 (H3N2) FOR PRODUCTION OF LIVE INFLUENZAL INTRANASAL VACCINE FOR ADULTS 1999
  • Kiseleva I.V.
  • Aleksandrova G.I.
  • Rudenko L.G.
  • Naumenko Z.S.
  • Klimov A.I.
 RU2159812C1
INFLUENZA VIRUS STRAIN A/47/PEKING/95/35 (H1N1) FOR PRODUCTION OF LIVE INFLUENZAL INTRANASAL VACCINE FOR BABIES 1999
  • Kiseleva I.V.
  • Aleksandrova G.I.
  • Rudenko L.G.
  • Naumenko Z.S.
  • Klimov A.I.
 RU2159810C1
STRAIN OF INFLUENZA VIRUS A/47/JOHANNESBURG/96/7/7 (H1N1) FOR PRODUCING LIVE ANTI-INFLUENZAL INTRANASAL VACCINE FOR CHILDREN 1998
  • Kiseleva I.V.
  • Aleksandrova G.I.
  • Rudenko L.G.
 RU2151185C1
STRAIN A/47/NANCHANG/95/13 (H3N2) FOR PRODUCTION OF LIVE ANTIINFLUENZA INTRANASAL VACCINE FOR CHILDREN 1997
  • Larionova N.V.
  • Aleksandrova G.I.
  • Rudenko L.G.
  • Klimov A.I.
  • Kiseleva I.V.
 RU2127757C1
INFLUENZA VIRUS A/17/WYOMING/03/8 (H3N2) STRAIN FOR PRODUCTION OF LIVING INFLUENZA INTRANASAL VACCINE FOR INFANTS AND ADULTS 2004
  • Aleksandrova Galina Ibragimovna
  • Rudenko Larisa Georgievna
  • Kiseleva Irina Vasil'Evna
  • Larionova Natal'Ja Valentinovna
 RU2285723C2
STRAIN OF INFLUENZA VIRUS A/47/NEW CALEDONIA/99/156 (H1N1) FOR PRODUCTION OF LIVE INFLUENZA INTRANASAL VACCINE FOR CHILDREN 2000
  • Kiseleva I.V.
  • Aleksandrova G.I.
  • Rudenko L.G.
  • Klimov A.I.
 RU2185437C1
INFLUENZA VIRUS STRAIN A/17/PEKING/95/25 (H1N1) FOR PRODUCTION OF LIVE INFLUENZAL INTRANASAL VACCINE FOR ADULTS 1999
  • Kiseleva I.V.
  • Aleksandrova G.I.
  • Rudenko L.G.
  • Naumenko Z.S.
  • Klimov A.I.
 RU2159811C1
STRAIN A/17/NANCHANG/95/4 (H3N2) FOR PRODUCTION OF LIVING AN ANTIINFLUENZA INTRANASAL VACCINE FOR ADULTS 1997
  • Kiseleva I.V.
  • Rudenko L.G.
  • Aleksandrova G.I.
  • Klimov A.I.
  • Larionova N.V.
 RU2128223C1
INFLUENZA VIRUS STRAIN A/47/PANAMA/99/234 (H3N2) FOR PRODUCING LIVE ANTI-INFLUENZA INTRANASAL VACCINE FOR CHILDREN 2003
  • Kiseleva I.V.
  • Aleksandrova G.I.
  • Rudenko L.G.
  • Klimov A.I.
 RU2248394C1
FIELD: medicinal virology 1996
  • Aleksandrova G.I.
  • Romanova Ju.R.
  • Rudenko L.G.
 RU2110278C1

RU 2 159 809 C1

Authors

Kiseleva I.V.

Aleksandrova G.I.

Rudenko L.G.

Naumenko Z.S.

Klimov A.I.

Dates

2000-11-27—Published

1999-05-25—Filed

download Download PDF read Similar patents