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2 285 723

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(51)

IPC

C12N7/00(2006-01-01)

A61K39/145(2006-01-01)

C12R1/93(2006-01-01)

(21) (22)

Application

2004137762/13, 2004-12-23

(24)

Start date

2004-12-23

(22)

Actual filing date

2004-12-23

(45)

Published

2006-10-20

(72)

Inventor

Aleksandrova Galina IbragimovnaRudenko Larisa GeorgievnaKiseleva Irina Vasil'EvnaLarionova Natal'Ja Valentinovna

(73)

Holder

Gu Institut Ehksperimental'Noj Meditsiny" Ramn Niiehm Ramn)

INFLUENZA VIRUS A/17/WYOMING/03/8 (H3N2) STRAIN FOR PRODUCTION OF LIVING INFLUENZA INTRANASAL VACCINE FOR INFANTS AND ADULTS Russian patent published in 2006 - IPC C12N7/00 A61K39/145 C12R1/93

Abstract RU 2285723 C2

FIELD: virology, medicine.

SUBSTANCE: claimed strain is obtained by genetic reassortment of A/Wyoming/3/03 (H3N2) epidemic virus with cold adapted A/Leningrad/134/17/57 (H2N2) strain, which represents attenuation donor, followed by selection in presence of serum for A/Leningrad/134/17/57 (H2N2) virus. Obtained strain is temperature sensitive and cold adapted. Reassortant has taken over epidemic virus two genes encoding hemagglutinine and neuraminidase surface proteins and six genes encoding non-glycosilated proteins from attenuation donor.

EFFECT: new strain for production of living influenza intranasal vaccine for infants and adults.

1 dwg, 3 tbl, 2 ex

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RU 2 285 723 C2

Authors

Aleksandrova Galina Ibragimovna

Rudenko Larisa Georgievna

Kiseleva Irina Vasil'Evna

Larionova Natal'Ja Valentinovna

Dates

2006-10-20—Published

2004-12-23—Filed