FIELD: medicine, endocrinology. SUBSTANCE: composition has human growth hormone as a complex compound with metal cation and biocompatible polymer. Molar ratio of metal cations to human hormone is > 4:1 and <or = 10:1. Zn (II) or Mg (II) can be used as metal cation. Polylactide, polyglycolide, copolymer of lactide and glycolide, polycaprolacton, polycarbonate and others can be used as preferable biocompatible polymer. In the process of complex preparing metal cations can be added as water-soluble salts. Components of composition provide stable and prolonged assurance of required levels of human growth hormone in blood. Invention can be used for treatment of patients suffering with dwarf state caused by hypophysis hypofunction. EFFECT: enhanced effectiveness and therapeutic effect of composition. 18 cl, 2 tbl, 7 ex
