FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to pharmaceutics, more specifically to a delivered pharmaceutical composition with controlled release of biologically active compounds to a subject, containing: a) a complex biologically active compound containing at least one basic functional group, and polyanion which is a hexahydroxycyclohexane derivative, containing at least two negative functional groups; and a pharmaceutically acceptable carrier containing biodegradable water-insoluble polymer.
EFFECT: invention provides a delivery system which stabilises biologically active compounds, regulates polymer degradation, limits spurt effect and maintains drug release within therapeutic limits of treatment length.
29 cl, 19 ex, 8 tbl
Authors
Dates
2010-05-27—Published
2005-08-11—Filed