FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to medicine and pharmacology, and represents an injected polymeric composition containing: a peptide agent salt produced by strong acid selected from a group consisting from hydrochloric acid, hydrobromic acid, hydroiodic acid, sulphuric acid, nitric acid, chromic acid, methanesulphonic acid, trifluoromethanesulphonic acid, trichloroacetic acid, dichloroacetic acid, bromo-acetic acid, chloroacetic acid, cyanoacetic acid, 2-chloropropanoic acid, 2-oxobutanoic acid, 2-chlorobutanoic acid, 4-cyanobutanoic acid, perchloric acid and phosphoric acid; water-insoluble biodegradable polymer; pharmaceutically acceptable organic solvent which dissolves biodegradable polymer and water or biological fluid miscible or dispersed, and optionally one or more pharmaceutically acceptable excipient where the peptide agent has an N-terminal which is not a primary amine and where the peptide agent contains at least one primary group.
EFFECT: invention provides higher stability and storage period of the declared composition.
24 cl, 17 ex, 8 tbl, 6 dwg
