BIOLOGICALLY-ACTIVE ADDITIVE Russian patent published in 2001 - IPC

FIELD: food and pharmaceutical industries. SUBSTANCE: biologically-active additive in the form of mixture of fate base with biomass of non-pathogenic microorganisms more precisely represents above-said biomass with number of viable cells within a range of 10¹-10¹¹, disintegrated to particle size no greater than 250 mcm and uniformly distributed throughout the bulk of fate base. Non-pathogenic microorganisms are selected from the family of Lactobacillus and/or Bificobacterium. and/or Streptococcus, and/or Propionibacterium, and/or Esterichia, and/or Saccharomyces, and/or brewer's yeast, and/or baker's yeast, and/or microorganism autolysate. Additive can contain, individually or in mixture: hydrogenated fat, vegetable oil (in particular, sunflower oil, peach oil, flax oil, or hempseed oil), butter, mixed fat, lanolin, spermaceti, wax, vaseline, paraffin, ceresin, vaseline oil, artificial vaseline, peresterified fats, confectionery fat, palmitin, palm olein, palm stearin, and cacao oil. Additive may further contain emulsifier and/or stabilizer, and/or structure-forming agent, and liquid and/or dry biologically-active agents, for instance lysozyme and/or interferon, and/or vitamins, and/or interleukin, and/or tumor necrosis factor (alpha), and/or immunoglobulins. The latter can be presented as mixture of IgA, IgG, and IgM. EFFECT: increased biological activity and storage stability. 12 cl, 3 cl