METHOD OF SYNTHESIS OF 1-ADAMANTYLALDEHYDE Russian patent published in 2001 - IPC

Abstract RU 2163591 C2

FIELD: organic chemistry, chemical technology. SUBSTANCE: invention relates to the field of synthesis of 1-adamantylaldehyde that can be used as a semiproduct for synthesis of functional adamantanes and biologically active substances also. Method involves the use of 1-adamantane carboxylic acid nitrile as the functional derivative that is reduced with product obtained by interaction of tin (II) chloride with hydrogen chloride in the presence of diethyl ether to yield 1-adamantylaldimine hexachlorostannic salt. The latter is treated with water excess to yield 1-adamantylaldehyde in the mole ratio of 1-adamantane carboxylic acid, tin chloride and diethyl ether = 1: (1.5-2.0): (6.2-7.0), respectively. EFFECT: simplified process, increased yield, absence of polymer in reaction products. 1 tbl, 8 ex

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RU 2 163 591 C2

Authors

Voloboev S.N.

Butenko L.N.

Novakov I.A.

Dates

2001-02-27Published

1999-04-06Filed