SUCCINIC ACID DERIVATIVES, SUCCINIC ACID-POLYSACCHARIDE DERIVATIVE, METHOD OF PREPARING SUCCINIC ACID-GLYCOSAMINOGLYCANE DERIVATIVE, METHOD OF PREPARING SUCCINIC ACID-POLYAMINOSACCHARIDE DERIVATIVE, AND METHOD OF PREPARING CROSS- LINKED SUCCINIC ACID-POLYSACCHARIDE DERIVATIVE Russian patent published in 2001 - IPC

FIELD: organic synthesis. SUBSTANCE: invention provides novel derivative of succinic acid containing photodimerizable cross-linking group and represented by any of formulas 1-3 or its salt: R¹-A-H (1), R¹-B-OH (2), R²-C-H (3), where R¹ denotes group of formula 4: (4), in which R³ and R⁴ are hydrogen atoms; R² denotes group of formula 5: (5), in which R³ and R⁴ are defined above and R⁵ is low alkyl group; fragment A-H expresses intramolecular residue of amino- and hydroxy-containing compound represented by any of formulas 6-9: -O-(CH₂)_n-NH₂ (6), wherein n is integer from 3 to 18, -(O-CH₂CH₂)_m-NH₂ (7), wherein m is integer from 2 to 10, -O-CHR⁶CH(COOR⁷)-NH₂ (8), wherein R⁶ is hydrogen and R⁷ is lower alkyl, and -O-(CH₂)_l-NHCO-CHR⁸-NH₂ (9), wherein l is integer from 2 to 18 and R⁸ is side chain of omega-amino acid, hydrogen, or lower alkyl; fragment B-OH expresses amino acid residue of general formula 10: -NH-(CH₂)_k-COOH (10), wherein k is integer from 1 to 18; and fragment C-H expresses amino acid residue of general formula 11 or 12: -CO-(CH₂)_k-NH₂ (11), wherein k corresponds to above definition, and -(COCHR⁹NH)_i-H (12), wherein i is integer from 1 to 6 and R⁹ is hydrogen atom. Compounds can be used as medicine-destination material possessing biocompatibility, bioabsorption, and other useful properties. EFFECT: extended choice of compounds suitable for medicinal applications. 26 cl, 61 ex