POLYPEPTIDES OR THEIR SALTS AND PHARMACEUTICAL COMPOSITION Russian patent published in 1997 - IPC

FIELD: medicine, peptides. SUBSTANCE: product: polypeptides of the formula (I): A₁-T_гр-Cys-Tyr-A₂-Cys--A₃-A₂--Gly--A₃--Cys-Tyr-A₂-A₂--Cys-A₁-NH₂, or their salts where: A₁ - arginine, arginylarginine; A₂ - arginine, lysine; A₃ - tyrosine, phenylalanine being cysteine residues can be located at positions 3 and 16 and at positions 4 and 12 can be linked through the disulfide bridge. Pharmaceutical composition has an effective amount of polypeptide (I) as an active component used at dose 10-5000 mg/kg human body mass per a day. Cysteine residues in polypeptide structure at positions 3 and 16 and 7 and 12 were linked through disulfide bridge. Synthesized polypeptides were used in medicine as antibacterial and antiviral (for example, as anti-HIV) agents. EFFECT: improved method of synthesis, enhanced effectiveness of polypeptides. 3 cl, 1 dwg, 4 tbl