SUBSTITUTED LIPOSACCHARIDES USED FOR TREATMENT AND PROPHYLAXIS OF ENDOTOXICOSIS Russian patent published in 2001 - IPC

Abstract RU 2170738 C2

FIELD: organic chemistry, medicine. SUBSTANCE: invention describes novel substituted liposaccharides of the formula (I) where R1 means the group of the formula (a) where J and K are linear C1-C15-alkyl; R2 means linear C5-C15-alkyl; R3 means the group of the formula (b) where A and B mean linear C1-C15-alkyl; R4 means the group of the formula (c) where each U and V means linear C2-C15-alkyl and W means linear C1-C5-alkyl; RA means R5-O-CH2- where R5 means linear C1-C5- -alkyl; R6 means hydroxy-group; A1 and A2 means the group of the formula (d) , or their pharmaceutically acceptable salts. Compounds can be used for prophylaxis and constructive treatment of patients with endotoxin effect including sepsis, septicemia, endotoxicosis and different forms of septic shock. EFFECT: new compounds indicated above, valuable medicinal properties. 14 cl

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RU 2 170 738 C2

Authors

Krist Vil'Jam Dzh.

Rossignol Dehniel P.

Kobajasi Seiti

Kavata Tsutomu

Dates

2001-07-20Published

1996-06-05Filed