FIELD: medicine. SUBSTANCE: described are new heterocyclic compounds of formula I: wherein R1 is carboxy or lower alkoxycarbonyl: R2 is phenyl or lower alkylphenyl; R3 is phenyl or lower alkylphenyl; A1 is lower alkylene; A2 is chemical bond or lower alkylene and Q is as defined in claims, or pharmaceutically acceptable salts thereof. Also described are intermediate compounds of formula II:
wherein R2,R3,A2,-Q- are as defined above; R4 is hydrogen or lower alkyl, or salts thereof. Invention is useful for preparing medicinals having inhibiting activity with respect to aggregation of thrombicytes and vasolidating activity. EFFECT: improved properties of the title compounds. 7 cl, 28 ex, 2 tbl
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Authors
Dates
2001-12-10—Published
1994-12-16—Filed