FIELD: biotechnology. SUBSTANCE: strain is obtained by insertion of the sequence encoding only structural proteins of the horse Venezuelan encephalomyelitis virus (full-size DNA-copy of total 26 S RNA) in thymidine kinase gene of commercial small pox virus strain under control of small pox virus protein 7.5 K promoter. The obtained strain provides full-value immune response with respect to the horse Venezuelan encephalomyelitis virus. In cells infected with the obtained strain glycoproteins of supercapsid envelope of this virus were expressed on their surface. Strain can be used for diagnosis and prophylaxis of the horse Venezuelan encephalomyelitis virus. EFFECT: preparing the strain indicated above. 2 cl, 2 dwg, 2 tbl
| Title |
Year |
Author |
Number |
| RECOMBINANT PLASMID DNA PC-NS3 PROVIDING INTEGRATION OF COMPLEX OF GENES C, PRM, E, NS1, NS 2A, NS 2B, NS3 OF TICK-BORNE ENCEPHALITIS VIRUS IN GENOME OF BOVINE VACCINE VIRUS AND RECOMBINANT STRAIN OF BOVINE VACCINE VIRUS EXPRESSING COMPLEX OF GENES C, PRM, E, NS1, NS 2A, NS2B, NS3 OF TICK-BORNE ENCEPHALITIS VIRUS IN IMMUNIZED ORGANISM CELLS |
1995 |
- Gajnullina M.N.
- Dmitriev I.P.
- Dobrikova E.Ju.
- Khromykh A.A.
- Ignat'Ev G.M.
- Pugachev K.V.
- Ageenko V.A.
- Vorob'Eva M.S.
- Pletnev A.G.
- Beljaev A.S.
- Sandakhchiev L.S.
|
RU2112038C1 |
| RECOMBINANT PLASMID DNA PURVGF DETERMINING SYNTHESIS OF SMALLPOX VIRUS STRAIN L-IVP GROWTH FACTOR TOGETHER WITH ESCHERICHIA COLI BETA-GALACTOSIDASE AND STRAIN OF BACTERIUM ESCHERICHIA COLI CONTAINING RECOMBINANT PLASMID DNA PURVGF - A PRODUCER OF SMALLPOX VIRUS STRAIN L-IVP GROWTH FACTOR |
1993 |
- Petrov V.S.
- Belavin P.A.
- Cheshenko N.V.
- Raspopin V.V.
- Patrushev N.A.
- Krendel'Shchikov A.V.
- Malygin Eh.G.
|
RU2089612C1 |
| VIRAL GENOME FRAGMENT OF CHICKEN K STRAIN VARIOLA WHICH CONTAINS THYMIDINE KINASE GENE, pTK1FPV AND pTK2FPV RECOMBINANT PLASMID DNAs WHICH CONTAIN THIS SEQUENCE, AND pINTFPV1 RECOMBINANT PLASMID DNA WHICH IS ABLE TO INTEGRATE INTO VIRAL GENOME OF CHICKEN VARIOLA |
1999 |
- Susloparov M.A.
- Pljasunov I.V.
- Bakhtina M.M.
- Susloparov I.M.
- Makhova N.M.
- Lokteva L.A.
|
RU2180352C2 |
| RECOMBINANT PLASMID DNA PTBI-HBSAG COMPRISING CHIMERIC GENE TBI-HBSAG UNDER CONTROL OF SMALLPOX VACCINE PROMOTER P7,5K AND STRAIN OF RECOMBINANT SMALLPOX VACCINE INDUCING IMMUNE RESPONSE AGAINST HIV AND HUMAN HEPATITIS B IN ANIMAL BODY |
2001 |
- Shchelkunov S.N.
- Rjazankin I.A.
- Ageenko V.A.
- Ignat'Ev G.M.
- Babkin I.V.
|
RU2194075C2 |
| RECOMBINANT PLASMID DNA PUL 32 HCMV DETERMINING EXPRESSION OF HUMAN CYTOMEGALOVIRUS GENE UL 32 FRAGMENT ENCODING HYDROPHILIC SITE OF BASIC MATRIX PROTEIN PP 150 IN ESCHERICHIA COLI BACTERIUM CELLS |
1998 |
|
RU2151801C1 |
| RECOMBINANT PLASMID DNA PUHBC ENCODING GENE OF HEPATITIS VIRUS B CORE ANTIGEN PROTEIN AND ENSURING TO EXHIBIT FOREIGN EPITOPES ON THE CORE SURFACE |
1995 |
- Karpenko L.I.
- Chikaev N.A.
- Il'Ichev A.A.
|
RU2121504C1 |
| RECOMBINANT PLASMID DNA PQ-F35 ENCODING FUSED POLYPEPTIDE F35 SHOWING ANTIGENIC AND IMMUNOGENIC PROPERTIES OF MARBURG VIRUS PROTEIN VP 35, METHOD OF ITS PREPARING AND STRAIN OF BACTERIUM ESCHERICHIA COLI - SUPERPRODUCER OF RECOMBINANT POLYPEPTIDE F35 |
1998 |
- Sorokin A.V.
- Razumov I.A.
- Kazachinskaja E.I.
- Kachko A.V.
- Ivanova A.V.
- Mishin V.P.
- Bukreev A.A.
- Belanov E.F.
- Loktev V.B.
- Netesov S.V.
|
RU2144565C1 |
| RECOMBINANT PLASMID DNA PTLS CONTAINING GENE OF SINGLE-STRANDED ANTIBODY AGAINST TICK-BORNE ENCEPHALITIS VIRUS AND STRAIN OF BACTERIUM ESCHERICHIA COLI AS PRODUCER OF SINGLE-STRANDED ANTIBODIES AGAINST TICK-BORNE ENCEPHALITIS VIRUS |
1998 |
- Nikolenko G.N.
- Tikunova N.V.
- Golovin S.Ja.
- Protopopova E.V.
- Loktev V.B.
- Il'Ichev A.A.
- Deev S.M.
|
RU2158309C2 |
| RECOMBINANT PLASMID DNA PKHBC-33 CONTAINING GENE OF HEPATITIS B VIRUS CORE ANTIGEN INVOLVING SEQUENCE OF THE MAIN NEUTRALIZING EPITOPE OF HEPATITIS B VIRUS SURFACE ANTIGEN (137-147) AND STRAIN OF BACTERIUM ESCHERICHIA COLI - A PRODUCER OF HEPATITIS B VIRUS CORE ANTIGEN WITH THE MAIN NEUTRALIZING EPITOPE OF HEPATITIS B VIRUS SURFACE ANTIGEN EXHIBITED ON ITS SURFACE |
1995 |
- Karpenko L.I.
- Chikaev N.A.
- Melamed N.V.
- Il'Ichev A.A.
- Bajborodin S.I.
|
RU2112039C1 |
| RECOMBINANT DNA PLASMID PGSDE1 ENCODING TICK-BORNE ENCEPHALITIS VIRUS PROTEIN E AND STRAIN OF ESCHERICHIA COLI - PRODUCER OF TICK-BORNE ENCEPHALITIS VIRUS PROTEIN E |
1997 |
- Netesova N.A.
- Belavin P.A.
- Malygin Eh.G.
- Rukavishnikov M.Ju.
|
RU2136754C1 |
