FIELD: biotechnology, microbiology. SUBSTANCE: invention relates to production of antibiotics by microbiological method. Producing culture is grown in the presence of sodium salt of [poly-(2,5-dihydroxyphenylene]-4-thiosulfoacid as a stimulating agent. Stimulating agent is added in the concentration 2-10 mcg/ml after 24 h of growing onset. Producers of penicillin, streptomycin, rifamycin B or rubomycin can be used as a producing culture. EFFECT: enhanced intensity of biosynthesis of antibiotics. 7 cl, 4 dwg
Title | Year | Author | Number |
---|---|---|---|
METHOD OF CEPHALOSPORIN C BIOSYNTHESIS WITH USING NEW ACREMONIUM CHRYSOGENUM STRAIN, RNCM NO F-4081D | 2009 |
|
RU2426793C2 |
STRAIN OF BACTERIA ESCHERICHIA COLI - A PRODUCER OF L-THREONINE | 0 |
|
SU1694643A1 |
METHOD OF ANTIBIOTIC KANAMYCIN PRODUCING | 1994 |
|
RU2084528C1 |
HIGH-ACTIVE CRYSTALLINE PREPARATION OF CYCLOSPORINE A AND METHOD FOR ITS PREPARING | 2004 |
|
RU2272643C2 |
STRAIN MICROMONOSPORA PURPUREA VAR VIOLACEA - A PRODUCER OF ANTIBIOTIC GENTAMYCIN, AND A METHOD OF GENTAMYCIN PRODUCING | 1991 |
|
RU2033426C1 |
PROCESS FOR PRODUCING L-TREONINE | 0 |
|
SU943282A1 |
METHOD OF PRODUCING PREPARATION USED FOR CONTROL OF PLANT SICKNESSES | 1998 |
|
RU2144292C1 |
METHOD OF AVERMECTIN PREPARING, STRAIN STREPTOMYCES AVERMITILIS - A PRODUCER OF AVERMECTIN | 1995 |
|
RU2098483C1 |
METHOD OF SELECTION OF HIGH-PRODUCING STRAIN - A PRODUCER OF OXYTETRACYCLINE AND THE STRAIN STREPTOMYCES RIMOSUS - A PRODUCER OF OXYTETRACYCLINE | 1995 |
|
RU2110576C1 |
STRAIN STREPTOMYCES FRADIAE NITSB 99 - PRODUCER OF TYLOSIN | 1999 |
|
RU2147319C1 |
Authors
Dates
2001-08-20—Published
2000-12-21—Filed