ANALOGS OF VITAMIN D, PHARMACEUTICAL COMPOSITION Russian patent published in 2001 - IPC

FIELD: organic chemistry, steroids, vitamins, pharmacy. SUBSTANCE: invention describes novel derivatives of vitamin D₃ of the formula (I) where R is -T, F or OH; R₂ is H, lower alkyl, halogen atom; X is =CH₂ or if R₂ is OH then X is (H,H) or =CH₂ and A means or -CH₂-CH₂-. These compounds induce differentiation and inhibit proliferation of cutaneous and cancer cells and can be used, in part, for treatment of patients with hyperproliferative skin diseases, neoplasma diseases, sebaceous gland diseases and states associated with skin damages by light radiation. EFFECT: enhanced effectiveness of treatment and prophylaxis, valuable medicinal properties of compounds. 12 cl, 6 tbl, 38 ex